Various metabolic processes produce volatile organic compounds (VOCs) and certain inorganic gases as byproducts. It is possible to compare the profiles of the unwell to those of a “healthy” population to use variations in emitted compounds as biomarkers to indicate certain conditions. This technique could be used to screen patients for kidney disease, diabetes, respiratory conditions, some forms of cancer, or other diseases. Breath analysis is a particularly useful technique because it is non-invasive and could be used to screen for conditions before more serious symptoms occur. This technique could also be used in a variety of other applications including monitoring anesthetics during surgery or assessing exposure after a pollution event. However, detecting small concentrations of such varied compounds has been difficult to do effectively using conventional technology. Rapid, comprehensive analysis is needed to properly implement breath analysis.
The NovaTest P300 can rapidly sample and analyze breath without the need for additional sampling equipment or sample preparation. The P300 is capable of detecting a wide range of compounds with high sensitivity in a single test, and the system automatically generates an instant report with calculated results. These features can be used to efficiently create a distinct patient profile onsite instead of waiting for laboratory results. Comparing a patient’s profile to a standard “healthy” profile can identify markers in the breath that could indicate certain conditions or diseases. This solution would greatly simplify screening, making it more accessible and common. The resulting ability to detect diseases earlier would also make treatments more effective and successful.